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Item number: Cay21557-5

EHop-016 is an inhibitor of the small Rho GTPases Rac1 and Rac3. It inhibits Rac1 activity in MDA-MB-435 breast cancer cells with an IC50 value of 1.1 µM in a Rac1 activation assay. At a concentration of 1 µM, EHop-016 inhibits 58% of Rac3 activity, and it inhibits Cdc42 activity but only at higher concentrations...

Keywords:	N4-(9-ethyl-9H-carbazol-3-yl)-N2-[3-(4-morpholinyl)propyl]-2,4-pyrimidinediamine
Application:	RAC1 / RAC3 inhibitor
CAS	1380432-32-5
MW:	430.6 D

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