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EHop-016
Item number: Cay21557-5
EHop-016 is an inhibitor of the small Rho GTPases Rac1 and Rac3. It inhibits Rac1 activity in MDA-MB-435 breast cancer cells with an IC50 value of 1.1 µM in a Rac1 activation assay. At a concentration of 1 µM, EHop-016 inhibits 58% of Rac3 activity, and it inhibits Cdc42 activity but only at higher concentrations...
| Keywords: | N4-(9-ethyl-9H-carbazol-3-yl)-N2-[3-(4-morpholinyl)propyl]-2,4-pyrimidinediamine |
| Application: | RAC1 / RAC3 inhibitor |
| CAS | 1380432-32-5 |
| MW: | 430.6 D |
From 76.00€
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EHop-016
Item number: TGM-T2427-100mg
Description: EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 µM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3. Target: Ras, Rho. Smiles: CCn1c2ccccc2c2cc(Nc3ccnc(NCCCN4CCOCC4)n3)ccc12. References: Montalvo-Ortiz BL, et al. J Biol Chem. 2012, 287(16), 13228-13238.
| Keywords: | EHop 016 |
| CAS | 1380432-32-5 |
| MW: | 430.55 D |
From 39.00€
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