Description: Mafenide hydrochloride (4-Aminomethylbenzenesulfonamide hydrochloride) is a sulfonamide that inhibits the enzyme carbonic anhydrase and is used as topical anti-infective, especially in burn therapy. Target: Carbonic Anhydrase, Antibiotic, Antibacterial. Smiles: Cl.NCc1ccc(cc1)S(=O)(=O)N. References:...

A sulfonamide antibiotic, active against clinical isolates of S. pyogenes, MSSA, MRSA, Enterococcus, Enterobacteriaceae, and Gram-negative bacilli from burn patients in an agar well diffusion assay (mean zone of inhibition = 24-37 mm) but not in a broth dilution assay with MIC values ranging from 250->5,000 µg/ml,...