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Macozinone
Macozinone

Item number: TGM-T3583-100mg

Description: Macozinone (PBTZ169) inhibits decaprenylphosphoryl-beta-d-ribose 2'-oxidase (DprE1), more efficiently than BTZ043. Target: DprE1, Antibacterial. Smiles: [O-][N+](=O)c1cc(cc2c1sc(nc2=O)N1CCN(CC2CCCCC2)CC1)C(F)(F)F. References: González-Martínez NA,et al. In Vivo Activity of the Benzothiazinones PBTZ169...
Keywords: PBTZ169
Application: DprE1 inhibitor
CAS 1377239-83-2
MW: 456.48 D
From 31.00€ *
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PBTZ169
PBTZ169

Item number: Cay22202-1

PBTZ169 is an antibiotic with antimycobacterial activity. It is an irreversible inhibitor of DprE1, an essential enzyme for cell wall synthesis in mycobacteria. PBTZ169 is active against M. tuberculosis in vitro (MIC = =0.19 ng/ml) without inducing cytotoxicity in Vero cells when used at concentrations up to 125 µM....
Keywords: 2-[4-(cyclohexylmethyl)-1-piperazinyl]-8-nitro-6-(trifluoromethyl)-4H-1,3-benzothiazin-4-one
Application: DprE1 inhibitor
CAS 1377239-83-2
MW: 456.5 D
From 44.00€ *
Review