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Item number: TGM-T1923-100mg

Description: BRD4770, a histone methyltransferase G9a inhibitor, induces cell senescence. Target: Histone Methyltransferase. Smiles: COC(=O)c1ccc2n(CCCc3ccccc3)c(NC(=O)c3ccccc3)nc2c1. References: Yuan Y, et al. ACS Chem Biol. 2012, 7(7), 1152-1157.

Application:	EHMT2 inhibitor
CAS	1374601-40-7
MW:	413.47 D

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BRD4770

Item number: Cay11787-1

BRD4770 is an inhibitor of euchromatin histone methyltransferase 2 (EHMT2), also known as G9a, decreasing di- and trimethylation on lysine 9 of histone 3 (EC50 = 5 µM). Through its effects on EHMT2, BRD4770 induces senescence in the pancreatic cancer cell line PANC-1 without initiating apoptosis. It also blocks both...

Keywords:	HMTase Inhibitor VI, 2-(benzoylamino)-1-(3-phenylpropyl)-1H-benzimidazole-5-carboxylic acid, methyl ester
Application:	EHMT2 inhibitor
CAS	1374601-40-7
MW:	413.5 D

From 44.00€ *

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