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Item number: Cay35899-1

Atogepant is an antagonist of the calcitonin gene-related peptide (CGRP) receptor (IC50 = 0.026 nM). It is selective for the CGRP receptor over the adrenomedullin receptors (AM1) and AM2, calcitonin (CT) receptor, amylin receptor 1 (AMY1), and AMY3 receptor (IC50s = >18,000, 400, 6,274, 2.4 and 1,418 nM,...

Keywords:	(3'S)-1',2',5,7-tetrahydro-N-[(3S,5S,6R)-6-methyl-2-oxo-1-(2,2,2-trifluoroethyl)-5-(2,3,6-trifluorophenyl)-3-piperidinyl]-...
Application:	CGRP receptor (CALCRL) antagonist
CAS	1374248-81-3
MW:	603.5 D

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