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EML4-ALK Kinase Inhibitor 1
Item number: Cay45387-1
EML4-ALK kinase inhibitor 1 is an inhibitor of the anaplastic lymphoma kinase (ALK) fusion protein EML4-ALK (IC50 = 1 nM). It inhibits the growth of Ba/F3 cells expressing EML4-ALK (IC50 = 9.7 nM). In vivo, EML4-ALK kinase inhibitor 1 (10 mg/kg) induces tumor regression in mice xenografted with NIH3T3 cells...
| Keywords: | 6-ethyl-5-[(trans-4-methoxycyclohexyl)amino]-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-2-pyr... |
| Application: | EML4-ALK inhibitor |
| CAS | 1373409-08-5 |
| MW: | 580.78 D |
From 133.00€
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EML4-ALK kinase inhibitor 1
Item number: TGM-T11184-100mg
Description: EML4-ALK kinase inhibitor 1 (EML4 ALK kinase inhibitor 1) is a potent oral active inhibitor of echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK), with an IC50 of 1 nM. Target: ALK. Smiles:...
| Keywords: | EML4-ALK kinase inhibitor 1, EML4 ALK kinase inhibitor 1 |
| Application: | EML4-ALK kinase inhibitor |
| CAS | 1373409-08-5 |
| MW: | 580.76 D |
From 83.00€
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