Description: N-dodecanoyl-L-Homoserine lactone (C12-HSL) is a quorum sensing (QS) signaling molecule that impacts biofilm formation in bioreactors through acyl homoserine lactone (AHL) mediated microbial communication. Target: Others. Smiles: CCCCCCCCCC CC(=O)N[C@H]1CCOC1=O. References: Tabraiz S, et al. Temperature...

Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. Controlling bacterial infections by quenching their quorum sensing systems is a promising field of study. The expression of specific target genes, such as transcriptional regulators...

Soluble in DMSO and dimethylformamide (approx. 30mg/ml). N-dodecanoyl-L-Homoserine lactone (C12-HSL) is a small diffusible signalling molecule involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism in bacteria. In addition to regulating bacterial functions, C12-HSL...