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Item number: Cay31116-1

BETP is a positive allosteric modulator of glucagon-like peptide 1 receptor (GLP-1R, EC50 = 0.66 µM in a reporter assay). It is selective for GLP-1R over GLP-2R, as well as glucose-dependent insulinotropic polypeptide, glucagon, and the parathyroid hormone receptors. BETP induces cAMP accumulation and intracellular...

Keywords:	2-(ethylsulfinyl)-4-[3-(phenylmethoxy)phenyl]-6-(trifluoromethyl)-pyrimidine
Application:	Positive allosteric GLP-1R modulator
CAS	1371569-69-5
MW:	406.4 D

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BETP

Item number: TGM-TQ0124-100mg

Description: BETP is an agonist of GLP-1 receptor (EC50s: 0.66 and 0.755 µM for human and rat GLP-1 receptor). Target: Glucagon Receptor. Smiles: CCS(=O)c1nc(cc(n1)C(F)(F)F)-c1cccc(OCc2ccccc2)c1. References: Sloop KW, et al. Novel small molecule glucagon-like peptide-1 receptor agonist stimulates insulin secretion...

Application:	Positive allosteric GLP-1R modulator
CAS	1371569-69-5
MW:	406.42 D

From 39.00€ *

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