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Pimecrolimus
Pimecrolimus

Item number: Cay13107-10

Pimecrolimus is a natural ascomycin macrolactam that binds to macrophilin-12 (FKBP-12) and inhibits calcineurin as well as prolyl isomerase (rotamase). Presumably through these actions, it blocks the activation of T cells by allogeneic dendritic cells (IC50 = 0.55 nM) without affecting dendritic cells. Moreover,...
Keywords: Elidel, SDZ-ASM 981,...
Application: Calcineurin inhibitor
CAS 137071-32-0
MW: 810.5 D
From 35.00€ *
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Pimecrolimus
Pimecrolimus

Item number: CDX-P0598-M010

White to beige powder. Soluble in DMSO (20mg/ml), DMF (20mg/ml) or ethanol (20mg/ml). Chemical. CAS: 137071-32-0. Formula: C43H68ClNO11. MW: 810.45. Synthetic. Pimecrolimus is a immunosuppressive natural ascomycin macrolactam that binds to macrophilin-12 (FKBP-12) and inhibits calcineurin as well as prolyl isomerase...
Keywords: Elidel, SDZ-ASM 981, 33-Epichloro-33-desoxyascomycin
CAS 137071-32-0
MW: 810,45 D
From 31.00€ *
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Pimecrolimus (Elidel, SDZ-ASM-981, D05480)
Pimecrolimus (Elidel, SDZ-ASM-981, D05480)

Item number: P4186-66.5

Pimecrolimus, a rapamycin (sirolimus) derivative, is a cell-selective inhibitor of inflammatory cytokines developed for the treatment of inflammatory skin diseases, such as allergic contact dermatitis, atopic dermatitis, plaque-type psoriasis, and irritant contact dermatitis. It reduces the production of...
CAS 137071-32-0
MW: 810.45
216.00€ *
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Pimecrolimus
Pimecrolimus

Item number: LKT-P3348.1

Calcineurin inhibitor, potential TRPV1 agonist.
Keywords: 33-epi-chloro-33-desoxyascomycin, Elidel, SDZ-ASM 981, SDZ ASM 981, SDZ-ASM-981, Picrolimus, ASM981, ASM-981, ASM 981,...
Application: Calcineurin inhibitor
CAS 137071-32-0
MW: 810.45 D
From 79.00€ *
Review