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Item number: Cay17652-10

BIIB-057 is a potent inhibitor of the non-receptor tyrosine kinase Syk (IC50 = 1 nM). It displays at least 80-fold selectivity for Syk over other kinases. BIIB-057 blocks B cell receptor-mediated cell signaling and activation in whole blood (IC50s = 0.27 and 0.28 µM, respectively), as well as Fc? receptor 1-mediated...

Keywords:	P505-15, PRT062607, PRT2607,...
Application:	Syk inhibitor
CAS	1370261-96-3
MW:	393.5 D

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