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Quiflapon
Item number: TGM-T16087-100mg
Description: Quiflapon (MK-591) causes cell apoptosis. Quiflapon is a selective and specific 5-lipoxygenase-activating protein (FLAP) inhibitor (IC50: 1.6 nM in a FLAP binding assay) and is also an effective and orally active Leukotriene biosynthesis (LT) inhibitor (IC50: 3.1 and 6.1 nM in intact human and elicited...
| Keywords: | MK-591 |
| Application: | FLAP inhibitor |
| CAS | 136668-42-3 |
| MW: | 587.17 D |
From 31.00€
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MK-0591
Item number: Cay37322-1
MK-0591 is an inhibitor of 5-lipoxygenase-activating protein (FLAP, IC50 = 1.6 nM for the human enzyme). It inhibits leukotriene B4 (LTB4, Cay-20110) biosynthesis in isolated rat neutrophils stimulated with the calcium ionophore A23187 (Cay-11016, IC50 = 6 nM) but does not inhibit 5-lipoxygenase (5-LO) in a...
| Keywords: | L-686,708, Quiflapon,... |
| Application: | FLAP inhibitor |
| CAS | 136668-42-3 |
| MW: | 587.2 D |
From 92.00€
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