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Item number: Cay37322-1

MK-0591 is an inhibitor of 5-lipoxygenase-activating protein (FLAP, IC50 = 1.6 nM for the human enzyme). It inhibits leukotriene B4 (LTB4, Cay-20110) biosynthesis in isolated rat neutrophils stimulated with the calcium ionophore A23187 (Cay-11016, IC50 = 6 nM) but does not inhibit 5-lipoxygenase (5-LO) in a...

Keywords:	L-686,708, Quiflapon,...
Application:	FLAP inhibitor
CAS	136668-42-3
MW:	587.2 D

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