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DG-172 (hydrochloride)
Item number: Cay19128-5
DG-172 is an orally available inverse agonist of PPARbeta/delta (IC50 = 27 nM), down-regulating transcription of ANGPTL4 in mouse myoblasts (IC50 = 9.5 nM). It alters the differentiation of bone marrow cells, augmenting GM-CSF-induced development into subsets of mature and immature dendritic cells. Inverse agonists...
| Keywords: | 2-bromo-alphaZ-[[4-(4-methyl-1-piperazinyl)phenyl]methylene]-benzeneacetonitrile, dihydrochloride |
| Application: | PPAR delta inverse agonist |
| CAS | 1361504-77-9 |
| MW: | 455.2 D |
From 44.00€
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DG172 dihydrochloride
Item number: TGM-T7821-100mg
Description: DG172 dihydrochloride (DG-172 dihydrochloride) is an antagonist of PPARbeta/delta(IC50 : 27 nM). Target: PPAR. Smiles: Cl.Cl.CN1CCN(CC1)c1ccc(\C=C(/C#N)c2ccccc2Br)cc1. References: Lieber S, et al. (Z)-2-(2-bromophenyl)-3-{[4-(1-methyl-piperazine)amino]phenyl}acrylonitrile (DG172): an orally bioavailable...
| Keywords: | DG172 (dihydrochloride), DG-172 dihydrochloride |
| Application: | PPAR delta inverse agonist |
| CAS | 1361504-77-9 |
| MW: | 455.2 D |
From 33.00€
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