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Item number: Cay45401-1

M435-1279 is an inhibitor of ubiquitin-conjugating enzyme E2T (UBE2T). It binds to UBE2T (Kd = 50.5 µM), inhibits UBE2T-mediated degradation of receptor for activated C kinase 1 (RACK1), and reduces hyperactive Wnt/beta-catenin signaling. M435-1279 reduces the viability of MKN45 and AGS gastric cancer cells when...

Keywords:	N-[4-(aminosulfonyl)phenyl]-1,2,5,6,7,8-hexahydro-4-hydroxy-2-oxo-[1]benzothieno[2,3-b]pyridine-3-carboxamide
Application:	UBE2T inhibitor
CAS	1359431-16-5
MW:	419.47 D

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M435-1279

Item number: TGM-T9500-100mg

Description: M435-1279 is a UBE2T inhibitor that blocks UBE2T-mediated degradation of RACK1, thereby inhibiting the hyperactivation of the Wnt/beta-catenin signaling pathway. Target: E1/E2/E3 Enzyme. Smiles: NS(=O)(=O)c1ccc(NC(=O)c2c(O)c3c4CCCCc4sc3[nH]c2=O)cc1. References: Yu Z, Jiang X, Qin L, Deng H, Wang J, Ren...

CAS	1359431-16-5
MW:	419.47 D

From 30.00€ *

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