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Item number: TGM-T16929-100mg

Description: SR2211 is a specific modulator and an inverse agonist of RORgamma(IC50 = 320 nM, Ki = 105 nM). Target: ROR. Smiles: OC(c1ccc(c(F)c1)-c1ccc(CN2CCN(Cc3ccncc3)CC2)cc1)(C(F)(F)F)C(F)(F)F. References: Kumar N, et al. Identification of SR2211: a potent synthetic RORgamma-selective modulator. ACS Chem Biol....

Application:	ROR gamma agonist
CAS	1359164-11-6
MW:	527.48 D

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SR 2211

Item number: Cay11972-1

Retinoic acid receptor-related nuclear receptor gamma (RORgamma) plays a central role in T cell differentiation, particularly in the differentiation of pro-inflammatory TH17 cells, which are implicated in autoimmune diseases like multiple sclerosis and rheumatoid arthritis. SR 2211 selectively binds RORgamma (Ki =...

Keywords:	2-fluoro-4'-[[4-(4-pyridinylmethyl)-1-piperazinyl]methyl]-alpha,alpha-bis(trifluoromethyl)-[1,1'-biphenyl]-4-methanol
Application:	ROR gamma agonist
CAS	1359164-11-6
MW:	527.5 D

From 52.00€ *

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