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Item number: Cay42187-10

An AMPA receptor positive allosteric modulator, increases glutamate-induced calcium influx in CHO cells expressing human AMPA receptors (EC50 = 3.3 µM), potentiates AMPA receptor-mediated currents in rat primary hippocampal neurons (EC50= 4.4 µM), ameliorates MK-801-induced working memory deficits in the radial arm...

Keywords:	NBI 1065845, 9-[4-(cyclohexyloxy)phenyl]-3,4- dihydro-7-methyl-pyrazino[2,1-c][1,2,4]thiadiazine, 2,2-dioxide
Application:	AMPA receptor positive allosteric modulator (PAM)
CAS	1358751-06-0
MW:	373.47 D

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