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ORY-2001
ORY-2001

Item number: Cay43663-1

An LSD1 and MAO-B inhibitor (IC50s = 0.101 and 0.073 µM, respectively), selective for LSD1 and MAO-B over MAO-A (IC50 = 5.47 µM) and LSD2, SMOX, and LAAO at 10 µM, as well as a panel of 19 additional epigenetic targets and a panel of 92 receptors, ion channels, enzymes, and transporters at 10 µM, induces...
Keywords: Vafidemstat, 5-amino-N-[(1R,2S)-2-[4-(phenylmethoxy)phenyl]cyclopropyl]-1,3,4-oxadiazole-2-methanamine
Application: LSD1 / MAO-B inhibitor
CAS 1357362-02-7
MW: 336.4 D
From 68.00€ *
Review
Vafidemstat
Vafidemstat

Item number: TGM-T17211-1mg

Description: Vafidemstat (ORY-2001) is a selective, orally active lysyl-histone demethylase (LSD1)/MAO-B inhibitor that crosses the blood-brain barrier for the study of neurological diseases. Target: MAO, Histone Demethylase. Smiles: Nc1nnc(CN[C@@H]2C[C@H]2c2ccc(OCc3ccccc3)cc2)o1. References: Antonijoan RM,et al....
Keywords: ORY-2001
CAS 1357362-02-7
MW: 336.39 D
From 141.00€ *
Review