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Palonosetron hydrochloride
Item number: TGM-T1156-100mg
Description: Palonosetron hydrochloride (RS 25259) is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting. Target: 5-HT Receptor. Smiles: Cl.O=C1N(C[C@H]2CCCc3cccc1c23)[C@@H]1CN2CCC1CC2. References: Wong EH, et al. Br J Pharmacol, 1995, 114(4), 851-859.
| Keywords: | RS 25259 197, Palonosetron HCl, RS 25259 |
| CAS | 135729-62-3 |
| MW: | 332.87 D |
From 46.00€
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Palonosetron (hydrochloride)
Item number: Cay16752-10
Palonosetron is an antagonist of the serotonin (5-HT) receptor subtype 5-HT3 (Ki = 0.04 nM). It is selective for 5-HT3 over 5-HT1A, 5-HT1D, 5-HT2A, and 5-HT2C receptors (Kis = >15.85 µM for all), as well as a panel of additional neurotransmitter receptors. Palonosetron inhibits 5-HT-induced contraction in isolated...
| Keywords: | RS 25259-197, 2-[(3S)-1-azabicyclo[2.2.2]oct-3-yl]-2,3,3aS,4,5,6-hexahydro-1H-benz[de]isoquinolin-1-one, monohydrochloride |
| Application: | 5-HT3-receptor antagonist |
| CAS | 135729-62-3 |
| MW: | 332.9 D |
From 100.00€
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