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Lin28 Inhibitor LI71
Item number: Cay41039-10
Lin28 inhibitor LI71 is an inhibitor of the protein-microRNA precursor interaction between the RNA-binding protein Lin28 and let-7. It binds to the cold-shock domain of Lin28 to inhibit let-7 binding and inhibits Lin28-mediated let-7 oligouridylation (IC50 = ~27 µM). Lin28 inhibitor LI71 (100 µM) increases the...
| Keywords: | 4-[(3aS,4R,9bR)-6-ethoxy-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl]-benzoic acid |
| Application: | Protein-microRNA precursor Lin28 -let-7 interaction inhibitor |
| CAS | 1357248-83-9 |
| MW: | 335.4 D |
From 172.00€
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LIN28 inhibitor LI71
Item number: TGM-T11850-100mg
Description: LIN28 inhibitor LI71 is a potent and cell-permeable compound that effectively abolishes LIN28-mediated oligouridylation, with an IC50 of 7 µM (micromolar). Target: Others. Smiles: [H][C@]12CC=C[C@@]1([H])c1cccc(OCC)c1N[C@H]2c1ccc(cc1)C(O)=O. References: Wang L, et al. Small-Molecule Inhibitors Disrupt...
| Application: | LIN28 inhibitor |
| CAS | 1357248-83-9 |
| MW: | 335.4 D |
From 131.00€
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