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Item number: Cay36105-1

AT-001 is an inhibitor of aldose reductase (IC50 = 28.9 pM). It reduces infarct area in streptozotocin-induced diabetic mice expressing human aldose reductase in a model of cardiomyopathy induced by ischemia-reperfusion injury when administered at a dose of 40 mg/kg.Formal Name:...

Keywords:	Caficrestat, 7,8-dihydro-8-oxo-7-[[5-(trifluoromethyl)-2-benzothiazolyl]methyl]-pyrazino[2,3-d]pyridazine-5-acetic acid
Application:	Aldose reductase inhibitor
CAS	1355612-71-3
MW:	421.4 D

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Aldose reductase-IN-1

Item number: TGM-T14175-100mg

Description: Aldose reductase-IN-1 (AT-001) is a aldose reductase inhibitor (IC50: 28.9 pM). Target: Others, Reductase. Smiles: OC(=O)Cc1nn(Cc2nc3cc(ccc3s2)C(F)(F)F)c(=O)c2nccnc12. References: ALDOSE REDUCTASE INHIBITORS AND USES THEREOF

Keywords:	Caficrestat, AT-001
Application:	Targets aldehyde reductase [EC:1.1.1.21] (AKR1B)
CAS	1355612-71-3
MW:	421.35 D

From 49.00€ *

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