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Item number: Cay14560-1

CYM 50260 is an agonist of sphingosine-1-phosphate receptor 4 (S1P4). It induces gene transcription in a reporter assay using U2OS cells expressing human S1P4 (EC50 = 45 nM). CYM 50260 (25 µM) inhibits collagen-induced increases in PDGF-AB secretion from, and phosphorylated heat shock protein 27 (Hsp27) levels in,...

Keywords:	2-chloro-3-[2-(2,4-dichlorophenoxy)ethoxy]-6-(fluoromethyl)-pyridine
Application:	Sphingosine 1-phosphate receptor 4 (S1PR4, EDG6) agonist
CAS	1355026-60-6
MW:	350.6 D

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CYM50260

Item number: TGM-T15031-100mg

Description: CYM50260 is a potent and highly selective agonist of the sphingosine-1-phosphate 4 receptor (S1P4-R, EC50= nM), exhibiting no activity against S1P1-R, S1P2-R, S1P3-R, and S1P5-R. Target: LPL Receptor, Others. Smiles: FCc1ccc(OCCOc2ccc(Cl)cc2Cl)c(Cl)n1. References: Guerrero M, et al. Discovery, design...

CAS	1355026-60-6
MW:	350.6 D

From 46.00€ *

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