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WEHI-345
Item number: Cay23023-5
WEHI-345 is an inhibitor of receptor-interacting protein kinase 2 (RIPK2, IC50 = 130 nM in a kinase assay using human recombinant RIPK2). It is selective for RIPK2 over RIPK1, 4, and 5 (Kds = 46, >10,000, >10,000, and >10,000 nM, respectively) and a panel of 95 kinases at a concentration of 1 µM. WEHI-345 reduces...
| Keywords: | N-[2-[4-amino-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-2-methylpropyl]-4-pyridinecarboxamide |
| Application: | RIPK2 inhibitor |
| CAS | 1354825-58-3 |
| MW: | 401.5 D |
From 85.00€
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WEHI-345
Item number: TGM-T3997-2mg
Description: WEHI-345 is a potent and selective RIPK2 inhibitor that modulates NOD signaling events while preventing inflammatory cytokine production. Target: RIP kinase. Smiles: Cc1ccc(cc1)-c1nn(c2ncnc(N)c12)C(C)(C)CNC(=O)c1ccncc1. References: Nachbur U, et al. A RIPK2 inhibitor delays NOD signalling events yet...
| Keywords: | WEHI345 |
| Application: | RIPK2 inhibitor |
| CAS | 1354825-58-3 |
| MW: | 401.46 D |
75.00€
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