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Item number: Cay36107-5

PF-3450074 (PF74) is an inhibitor of HIV-1 capsid protein. It reduces viral infectivity in HeLa cells infected with wild-type HIV-1 but not P38A, E45A, Q63A/Q67A, or Q219A capsid protein mutant HIV-1, simian immunodeficiency virus, or murine leukemia virus when used at a concentration of 10 µM. PF74 (0.62-10 µM)...

Keywords:	PF74, 2-methyl-N-[(1S)-2-(methylphenylamino)-2-oxo-1-(phenylmethyl)ethyl]-1H-indole-3-acetamide
Application:	HIV-1 capsid protein inhibitor
CAS	1352879-65-2
MW:	425.5 D

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NEW

PF-3450074

Item number: TGM-T16500-100mg

Description: PF-3450074 (PF-74) acts at an early stage of HIV-1 infection inhibits viral replication by directly competing with the binding of CPSF6 (nuclear host factors cleavage and polyadenylation specific factor 6) and NUP153 (nucleoporin 153), and blocks the uncoating, assembly, and the reverse transcription...

Keywords:	PF-74
Application:	HIV-1 capsid protein inhibitor
CAS	1352879-65-2
MW:	425.52 D

From 29.00€ *

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