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Item number: TGM-T13675-100mg

Description: Elacestrant dihydrochloride (DA-DKRAD1901 dihydrochloride) is an orally available selective estrogen receptor degrader with IC50s of 48 for ERalpha and 870 nM for ERbeta, respectively. Target: Estrogen/progestogen Receptor. Smiles: Cl.Cl.CCNCCc1ccc(CN(CC)c2cc(OC)ccc2[C@@H]2CCc3cc(O)ccc3C2)cc1....

Keywords:	RAD1901 dihydrochloride
Application:	Targets estrogen receptor alpha (ESR1, NR3A1)
CAS	1349723-93-8
MW:	531.56 D

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Elacestrant (hydrochloride)

Item number: Cay37298-1

Elacestrant is a selective estrogen receptor degrader (SERD). It selectively binds to estrogen receptor alpha (ERalpha) over ERbeta (IC50s = 48 and 870 nM, respectively) and reduces ERalpha levels in MCF-7 cells (EC50 = 0.6 nM). Elacestrant reduces MCF-7 proliferation induced by 17beta-estradiol (E2, Cay-10006315)...

Keywords:	RAD901, 6R-[2-[ethyl[[4-[2-(ethylamino)ethyl]phenyl]methyl]amino]-4-methoxyphenyl]-5,6,7,8-tetrahydro-2-naphthalenol,...
Application:	Selective estrogen receptor degrader, SERD
CAS	1349723-93-8
MW:	531.6 D

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