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Item number: Cay29521-10

8-M-PDOT is a melatonin receptor 2 (MT2) agonist (Ki = 1.12 nM). It is 5.2-fold selective for MT2 over MT1 receptors in a radioligand binding assay. Striatal microinfusion of 8-M-PDOT (10 µg/µl) increases the percentage of time spent in the open arms of the elevated plus maze, indicating anxiolytic-like activity, in...

Keywords:	AH 002, N-(1,2,3,4-tetrahydro-8-methoxy-2-naphthalenyl)-propanamide
Application:	Melatonin receptor type 1B (MTNR1B) agonist
CAS	134865-70-6
MW:	233.3 D

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8-M-PDOT

Item number: TGM-T10198-10mg

Description: 8-M-PDOT (AH-002) is a selective and potent melatonin MT2 receptor agonist that also inhibits MT1 receptors. 8-M-PDOT exhibits anxiolytic activity and can be used to study MT2-induced neuropathic pain. Target: MT Receptor. Smiles: CCC(=O)NC1CCc2cccc(OC)c2C1. References: Noseda AC, et al. REM sleep...

Keywords:	8-Methoxy-2-propionamidotetralin, AH-002
CAS	134865-70-6
MW:	233.31 D

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