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GSK621
Item number: TGM-T6854-100mg
Description: GSK621 is a specific and potent AMPK activator. Target: Autophagy, Apoptosis, AMPK. Smiles: COc1cccc(c1)-n1c(=O)[nH]c2cc(Cl)n(-c3ccc(cc3)-c3cccc(OC)c3O)c2c1=O. References: Sujobert P, et al. Cell Rep. 2015, 11(9), 1446-1457.
| Application: | AMPK activator |
| CAS | 1346607-05-3 |
| MW: | 489.91 D |
From 49.00€
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GSK621
Item number: Cay19155-5
GSK621 is an activator of AMP-activated protein kinase (AMPK). It has been shown to increase phosphorylation at AMPKalpha T172, a marker of AMPK activation, in both acute myeloid leukemia (AML) cell lines and primary AML samples. GSK621 is reported to reduce the proliferation of AML cell lines (IC50s = 13-30 µM),...
| Keywords: | 6-chloro-5-(2'-hydroxy-3'-methoxy[1,1'-biphenyl]-4-yl)-3-(3-methoxyphenyl)-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione |
| Application: | AMPK activator |
| CAS | 1346607-05-3 |
| MW: | 489.9 D |
From 78.00€
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