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Item number: Cay45303-1

An 11beta-HSD1 inhibitor (IC50s = 2.9 and 1.6 nM for the human and mouse enzymes, respectively), reduces postprandial blood glucose, HbA1c, blood LDL and total cholesterol, and blood triglyceride levels in an ob/ob mouse model of type 2 diabetes and metabolic syndrome at 20 mg/kg orally. SMILES:...

Keywords:	2-[(2R)-4-[2-fluoro-4-(methylsulfonyl)phenyl]-2-methyl-1-piperazinyl]-N-[5-hydroxytricyclo[3.3.1.1...
Application:	11beta-HSD1 inhibitor
CAS	1346554-47-9
MW:	543.66 D

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