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ML-154
Item number: Cay30200-1
ML-154 is an antagonist of the neuropeptide S receptor (NPSR, IC50 = 3.5 nM). It is selective for NPSR over arginine vasopressin (AVP) receptor V1B, as well as a panel of 55 receptors, channels, and transporters at 10 µM. ML-154 reduces NPS-induced calcium mobilization, cAMP formation, and ERK activation with IC50...
| Keywords: | NCGC84, 3-(diphenylphosphinothioyl)-2-methyl-1-[(2E)-3-phenyl-2-propen-1-yl]-imidazo[1,2-a]pyridinium, monobromide |
| Application: | Neuropeptide S receptor (NPSR1) antagonist |
| CAS | 1345964-89-7 |
| MW: | 545.5 D |
From 94.00€
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ML 154
Item number: TGM-T22994-100mg
Description: ML 154 is a potent neuropeptide S receptor (NPSR) antagonist. Target: Neuropeptide Y Receptor. Smiles: CC1=C(P(C2=CC=CC=C2)(C3=CC=CC=C3)=S)[N+]4=CC=CC=C4N1C/C([H])=C([H])/C5=CC=CC=C5.[Br-]. References: Batran RZ, et al. New quinolone derivatives as neuropeptide S receptor antagonists: Design, synthesis,...
| CAS | 1345964-89-7 |
| MW: | 545.47 D |
From 54.00€
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