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BIMU 8
Item number: Cay30964-1
BIMU 8 is an agonist of the serotonin (5-HT) receptor subtype 5-HT4 (Ki = 69 nM). It also binds 5-HT3 receptors (Ki = 0.36 nM). It stimulates cAMP formation in primary mouse embryonic colliculi neurons with an EC50 value of 72 nM. BIMU 8 (30, 40, and 60 nmol/animal, i.c.v.) induces acetylcholine release in the rat...
| Keywords: | 2,3-dihydro-N-[(3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl]-3-(1-methylethyl)-2-oxo-1H-benzimidazole-1-carboxamide,... |
| Application: | 5-HT4 receptor agonist |
| CAS | 134296-40-5 |
| MW: | 378.9 D |
From 60.00€
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BIMU 8
Item number: TGM-T21946-100mg
Description: BIMU 8 is a selective agonist of 5-HT4 with EC50s of 18 nM, 77 nM, and 540 nM for wild-type 5HT4 receptor, T3.36A, and W6.48A mutant 5-HT4. Target: 5-HT Receptor. Smiles: Cl.CC(C)n1c2ccccc2n(C(=O)N[C@@H]2C[C@@H]3CC[C@H](C2)N3C)c1=O. References: H Pan , et al. 5-HT1A and 5-HT4 receptors mediate...
| CAS | 134296-40-5 |
| MW: | 378.9 D |
From 77.00€
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