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RKI-1447
Item number: Cay16278-5
RKI-1447 is an inhibitor of the Rho-associated kinases ROCK1 and 2 (IC50s = 14.5 and 6.2 nM, respectively) that functions by binding to the ATP binding site of the kinase. In cancer cells, RKI-1447 at a concentration of 100 nM has been found to suppress the activation of ROCK substrates myosin light chain (MLC)-2...
| Keywords: | N-[(3-hydroxyphenyl)methyl]-N'-[4-(4-pyridinyl)-2-thiazolyl]-urea |
| Application: | ROCK inhibitor |
| CAS | 1342278-01-6 |
| MW: | 326.4 D |
From 82.00€
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RKI-1447
Item number: LKT-R4132.1
ROCK1/2 inhibitor.
| Keywords: | RKI1447 |
| Application: | ROCK1/2 inhibitor |
| CAS | 1342278-01-6 |
| MW: | 326.37 D |
From 77.00€
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