2 products were found matching "1340593-59-0"!
No results were found for the filter!
VT-1161
Item number: Cay43577-1
VT-1161 is an antifungal agent. It selectively binds to C. albicans lanosterol 14-alpha-demethylase (Kd = 39 nM), also known as cytochrome P450 (CYP) isoform CYP51, over human lanosterol 14-alpha-demethylase at 86 µM and does not inhibit human CYP2C9, CYP2C19, or CYP3A4 (IC50s = 99, 72, and 65 µM, respectively)....
| Keywords: | Oteseconazole,... |
| Application: | Antifungal agent, ergosterol biosynthesis inhibitor |
| CAS | 1340593-59-0 |
| MW: | 527.4 D |
From 97.00€
*
Oteseconazole
Item number: TGM-T16412-100mg
Description: Oteseconazole (VT-1161) is an orally active anti-fungal agent. Oteseconazole displays no obvious effect on human CYP51. It also potently binds to and inhibits Candida albicans CYP51 (Kd, <39 nM). Target: P450, Antifungal. Smiles: O[C@@](Cn1cnnn1)(c1ccc(F)cc1F)C(F)(F)c1ccc(cn1)-c1ccc(OCC(F)(F)F)cc1....
| Keywords: | VT-1161 |
| Application: | Targets sterol 14alpha-demethylase [EC:1.14.14.154 1.14.15.36] (CYP51) |
| CAS | 1340593-59-0 |
| MW: | 527.39 D |
From 87.00€
*
