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BMS-5
Item number: TGM-T4598-100mg
Description: BMS-5 (LIMKi 3) is a highly potent LIMK inhibitor, exhibiting IC50 values of 7 nM for LIMK1 and 8 nM for LIMK2. Target: LIM Kinase. Smiles: CC(C)C(=O)Nc1ncc(s1)-c1cc(nn1-c1c(Cl)cccc1Cl)C(F)F. References: Ross-Macdonald P, et al. Identification of a nonkinase target mediating cytotoxicity of novel kinase...
| Keywords: | BMS5, LIMKi 3 |
| Application: | LIMK1 / LIMK2 inhibitor |
| CAS | 1338247-35-0 |
| MW: | 431.29 D |
From 37.00€
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BMS-5
Item number: SYN-1024-M001
Soluble in DMSO. Kinases, such as LIM kinase 1 (LIMK1) and LIM kinase 2 (LIMK2), have been identified as participating in signal pathways affecting actin dynamics by deactivating cofilin. Over expression of LMK1 has been found in invasive breast and prostate cancer cell lines and suppression of LIMK 2 expression has...
| Keywords: | BMS5 |
| Application: | LIMK1 / LIMK2 inhibitor |
| CAS | 1338247-35-0 |
| MW: | 431,3 D |
From 123.00€
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BMS-5
Item number: Cay21072-1
BMS-5 is a potent inhibitor of activated LIM domain kinases LIMK1 and LIMK2 with IC50 values of 7 and 8 nM, respectively. LIMK1 and LIMK2 participate in signal pathways affecting actin dynamics by deactivating cofilin. This compound can be used to study the role of activated LIMK isoforms in the signaling of Rho...
| Keywords: | LIM Kinase Inhibitor I, LIMKi 3,... |
| Application: | LIMK1 / LIMK2 inhibitor |
| CAS | 1338247-35-0 |
| MW: | 431.3 D |
From 66.00€
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