2 products were found matching "1337531-36-8"!

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Item number: Cay17376-1

GSK2606414 is an orally available, selective protein kinase R-like ER kinase (PERK) inhibitor with an IC50 value of 0.4 nM. It can inhibit thapsigargin-induced PERK phosphorylation in lung carcinoma A549 cells and attenuates subcutaneous pancreatic human tumor xenograft growth in mice. Because PERK mediates the...

Keywords:	1-[5-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydro-1H-indol-1-yl]-2-[3-(trifluoromethyl)phenyl]-ethanone
Application:	EIF2AK3?/ PERK inhibitor
CAS	1337531-36-8
MW:	451.4 D

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GSK-2606414

Item number: SYN-1201-M001

Soluble in DMSO or ethanol. GSK2606414 is an orally available, potent, and selective PERK inhibitor with IC(50) of 0.4nM, displaying at least 100-fold selectivity over the other EIF2AKs assayed Target: PERK , Kinase Group: Other , Substrate: Serine-Threonine

Keywords:	GSK-2606414
Application:	EIF2AK3 / PERK inhibitor
CAS	1337531-36-8
MW:	451,4 D

From 119.00€ *

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