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Q203
Item number: TGM-T5400-100mg
Description: Q203 (Telacebec) is a novel potent anti-tuberculosis agent targeting cytochrome b subunit qcrB and inhibits M. tuberculosis H37Rv (MIC50: 2.7 nM). Target: Antibiotic, Antibacterial. Smiles: CCc1nc2ccc(Cl)cn2c1C(=O)NCc1ccc(cc1)N1CCC(CC1)c1ccc(OC(F)(F)F)cc1. References: Pethe K, et al. Discovery of Q203,...
| Keywords: | IAP6, Telacebec |
| Application: | Antibacterial (tuberculostatic) |
| CAS | 1334719-95-7 |
| MW: | 557.01 D |
From 46.00€
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Q203
Item number: Cay37323-1
Q203 is an imidazopyridine amide antibiotic. It is active against M. tuberculosis and M. ulcerans (MIC50s = 2.7 and 0.86 nM, respectively). Q203 binds to the oxidation site on mitochondrial complex III, also known as cytochrome bc1 complex, and disrupts ATP synthesis in M. tuberculosis (IC50 = 1.1 nM). It reduces...
| Keywords: | Telacebec,... |
| Application: | Imidazopyridine amide antibiotic, antibacterial (tuberculostatic) |
| CAS | 1334719-95-7 |
| MW: | 557 D |
From 78.00€
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