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(S)-MG132
(S)-MG132

Item number: Cay10012628-5

The ubiquitin-proteasome pathway plays an integral role in the selective degradation of intracellular proteins. While important for clearing damaged or misfolded proteins, this proteolytic pathway also regulates the availability of key proteins involved in the control of inflammatory processes, cell cycle...
Keywords: Z-Leu-Leu-Leu-CHO, N-[(phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-formyl-3-methylbutyl]-L-leucinamide
Application: Proteasome inhibitor
CAS 133407-82-6
MW: 475.6 D
From 27.00€ *
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-10 %
MG-132
MG-132

Item number: AG-CP3-0011-M005

Soluble in DMSO or ethanol. Potent, cell permeable and selective, reversible proteasome inhibitor. Blocks degradation of short-lived proteins and induces a heat shock response. NF-kappaB activation inhibitor through IkappaB degradation. Cell permeable, reversible peptide aldehyde inhibitor. Calpain and cathepsin...
Keywords: Z-Leu-Leu-Leu-CHO, Z-LLL-CHO, Carbobenzoxy-L-leucyl-L-leucyl-L-leucinal, MG132
Application: Proteasome inhibitor
CAS 133407-82-6
MW: 476 D
22.00€ * From 19.80€ *
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MG132
MG132

Item number: LKT-M2400.5

MG-132 is a proteasome inhibitor that exhibits anti-fibrotic and anti-osteoarthritic activities. In renal interstitial fibroblasts, MG-132 inhibits proliferation and induces apoptosis by activating p53, p21, caspase 3, and Bax. MG-132 also inhibits skeletal muscle atrophy in animal models of chronic obstructive...
Keywords: MG-132
Application: Proteasome inhibitor
CAS 133407-82-6
MW: 475.62 D
From 180.00€ *
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