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rac-Benpyrine
rac-Benpyrine

Item number: Cay36680-1

rac-Benpyrine is an inhibitor of the protein-protein interaction between TNF-alpha and TNF receptor 1 (TNFR1, IC50 = 0.109 µM). It reduces TNF-alpha-induced cytotoxicity in L-929 fibroblasts when used at a concentration of 10 µM, as well as prevents nuclear translocation of NF-kappaB in RAW 264.7 macrophages....
Keywords: 1-(phenylmethyl)-4-(9H-purin-6-ylamino)-2-pyrrolidinone
Application: TNF-alpha-TNFR1 protein-protein interaction inhibitor
CAS 1333714-43-4
MW: 308.3 D
From 77.00€ *
Review
(Rac)-Benpyrine
(Rac)-Benpyrine

Item number: TGM-T8692-100mg

Description: (Rac)-Benpyrine is a potent and orally active inhibitor of TNF-alpha. Target: TNF. Smiles: O=C1CC(CN1Cc1ccccc1)Nc1ncnc2[nH]cnc12. References: Hua Li, et al. Compound with TNF- alpha inhibitory activity and application. CN111320630A.
Application: TNF-alpha-TNFR1 protein-protein interaction inhibitor
CAS 1333714-43-4
MW: 308.34 D
From 40.00€ *
Review