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Gö 6983
Item number: Cay13311-1
Gö 6983 inhibits several isoforms of protein kinase C (PKC, IC50 = 7, 7, 6, 10, 60, and 20,000 nM for PKCalpha, PKCbeta, PKCgamma, PKCdelta, PKCzeta, and PKCµ, respectively). It provides cardioprotective effects in myocardial ischemia/reperfusion by attenuating contractile dysfunction.Formal Name:...
| Keywords: | 3-[1-[3-(dimethylamino)propyl]-5-methoxy-1H-indol-3-yl]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione |
| Application: | PKC inhibitor |
| CAS | 133053-19-7 |
| MW: | 442.5 D |
From 61.00€
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Go 6983
Item number: TGM-T6313-100mg
Description: Go 6983, a pan-PKC inhibitor, targets PKCalpha, PKCbeta, PKCgamma, PKCdelta, and PKCzeta, with IC50 values of 7 nM, 7 nM, 6 nM, 10 nM, and 60 nM, respectively. Target: PKC. Smiles: COc1ccc2n(CCCN(C)C)cc(C3=C(C(=O)NC3=O)c3c[nH]c4ccccc34)c2c1. References: Gschwendt M, et al. FEBS Lett, 1996, 392(2), 77-80.
| Keywords: | Goe 6983 |
| CAS | 133053-19-7 |
| MW: | 442.51 D |
From 37.00€
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