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Bisindolylmaleimide I
Bisindolylmaleimide I

Item number: Cay13298-5

Bisindolylmaleimide I (BIM I) is a highly selective, cell-permeable, and reversible PKC inhibitor (Ki = 14 nM) that is structurally similar to the poorly selective PKC inhibitor staurosporine (Cay-81590). It acts as a competitive inhibitor for the ATP binding site of PKC and shows high selectivity for PKCalpha,...
Keywords: BIM I, GF 109203X, Gö 6850, 3-[1-[3-(dimethylamino)propyl]-1H-indol-3-yl]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione
Application: PKC inhibitor
CAS 133052-90-1
MW: 412.5 D
From 115.00€ *
Review
Bisindolylmaleimide I
Bisindolylmaleimide I

Item number: AG-CR1-0009-M001

Cell permeable kinase inhibitor with improved selectivity for protein kinase C (PKC) (Ki = 10 nM), Competetive inhibitor for the ATP-binding site of PKC, Anti-inflammatory, Binds to P-glycoprotein, Telomerase activity inhibitor, Potent glycogen synthase kinase-3 (GSK-3) inhibitor, Inhibits necrosis, Blocks hERG...
Keywords: GF-109203X, Gö 6850
Application: PKC inhibitor
CAS 133052-90-1
MW: 412,5 D
From 66.00€ *
Review