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CAIX Inhibitor S4
Item number: TGM-T36758-100mg
Description: CAIX Inhibitor S4 (S4) is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively. The Kis for CA II and CA I are 546 and 5600 nM. Target: Carbonic Anhydrase. Smiles: Cc1cc(C)cc(NC(=O)Nc2ccc(OS(N)(=O)=O)cc2)c1. References: Gieling et al (2012) Antimetastatic effect...
| Keywords: | S4 |
| Application: | CAIX inhibitor |
| CAS | 1330061-67-0 |
| MW: | 335.38 D |
From 34.00€
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CAIX Inhibitor S4
Item number: Cay31119-10
CAIX inhibitor S4 is an inhibitor of carbonic anhydrase IX (CAIX, Ki = 0.007 µM for the recombinant human enzyme). It is selective for CAIX over CAI and CAII but does inhibit CAXII (Kis = 5.6, 0.55, and 0.002 µM, respectively). CAIX inhibitor S4 inhibits proliferation of HT-29 and MDA-MB-231, but not HCT116, cancer...
| Keywords: | sulfamic acid, 4-[[[(3,5-dimethylphenyl)amino]carbonyl]amino]phenyl ester |
| Application: | Carbonic anhydrase IX inhibitor |
| CAS | 1330061-67-0 |
| MW: | 335.4 D |
From 111.00€
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