2 products were found matching "1327167-19-0"!
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BPR1J-097
Item number: Cay29805-10
BPR1J-097 is an inhibitor of FMS-related tyrosine kinase 3 (FLT3, IC50 = 11 nM). It is selective for FLT3 over FLT1, KDR, Aurora A, and Aurora B kinases (IC50s = 211, 129, 340, and 876 nM, respectively). BPR1J-097 inhibits FLT3 activity and phosphorylation of STAT5 in MV4-11 acute myeloid leukemia (AML) cells...
| Keywords: | 4-(4-methyl-1-piperazinyl)-N-[5-[3-[(phenylsulfonyl)amino]phenyl]-1H-pyrazol-3-yl]-benzamide |
| Application: | FLT3 inhibitor |
| CAS | 1327167-19-0 |
| MW: | 516.6 D |
From 78.00€
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BPR1J-097
Item number: TGM-T2272-100mg
Description: BPR1J-097) is a novel FLT-3 inhibitor(IC50: 11±7 nM) with promising in vivo anti-tumor activities. It also inhibits FLT-3 D835Y (IC50: 3 nM). Target: FLT. Smiles: CN1CCN(CC1)c1ccc(cc1)C(=O)Nc1cc([nH]n1)-c1cccc(NS(=O)(=O)c2ccccc2)c1. References: Lin WH, et al. Br J Y. 2012 Jan 31,106(3):475-81.
| Keywords: | BPR1J097 |
| Application: | FLT3 inhibitor |
| CAS | 1327167-19-0 |
| MW: | 516.61 D |
From 48.00€
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