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Cinnamyl-3,4-dihydroxy-alpha-Cyanocinnamate

Item number: Cay10858-10

Cinnamyl-3,4-dihydroxy-alpha-cyanocinnamate (CDC) is an inhibitor of 5-lipoxygenase (5-LO, IC50 = 15 nM). It is selective for 5-LO over 12-LO and 15-LO (IC50s = 500 and 300 nM, respectively). CDC inhibits 5-LO product formation induced by the calcium ionophore A23187 (Cay-11016) in isolated human polymorphonuclear...

Keywords:	CDC, (2E)-2-cyano-3-(3,4-dihydroxyphenyl)-2-propenoic acid, 3-phenyl-2-propen-1-yl ester
Application:	5-lipoxygenase inhibitor
CAS	132465-11-3
MW:	321.3 D

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