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Item number: Cay17721-10

TC-G 1006 is a sphingosine-1-phosphate receptor 1 (S1P1) agonist. It selectively induces calcium mobilization in cells expressing S1P1 over cells expressing S1P2, S1P3, S1P4, or S1P5 (EC50s = 0. >25, >25, >50, and 4. µM, respectively). TC-G 1006 (0. 1, and 3 mg/kg) reduces the number of circulating lymphocytes in...

Keywords:	4-methoxy-N-[[[2-(trifluoromethyl)[1,1'-biphenyl]-4-yl]amino]carbonyl]-3-pyridinecarboxamide
Application:	S1P1 agonist
CAS	1324003-64-6
MW:	415.4 D

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S1P1 Agonist III

Item number: TGM-T16833-100mg

Description: S1P1 Agonist III is an effective and orally active S1P1 agonist (EC50: 18 nM). Target: Others. Smiles: COc1ccncc1C(=O)NC(=O)Nc1ccc(-c2ccccc2)c(c1)C(F)(F)F. References: Harrington PE, et al. Optimization of a Potent, Orally Active S1P1 Agonist Containing a Quinolinone Core. ACS Med Chem Lett. 2011 Nov...

CAS	1324003-64-6
MW:	415.37 D

849.00€ *

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