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Iberdomide
Item number: Cay22615-1
Iberdomide is a modulator of cereblon, a substrate receptor in the CRL4 ubiquitin ligase complex, that has an IC50 value of 60 nM in a competitive TR-FRET assay. In the same assay, it has a higher affinity for cereblon than the related modulators lenalidomide (Cay-14643, IC50 = 1,500 nM) and pomalidomide (Cay-19877,...
| Keywords: | CC-220, 3S-[1,3-dihydro-4-[[4-(4-morpholinylmethyl)phenyl]methoxy]-1-oxo-2H-isoindol-2-yl]-2,6-piperidinedione |
| Application: | Cereblon modulator |
| CAS | 1323403-33-3 |
| MW: | 449.5 D |
From 51.00€
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Iberdomide
Item number: TGM-T7791-25mg
Description: Iberdomide (CC-220) is a modulator of cereblon( IC50 value of 60 nM in a competitive TR-FRET assay). Target: Apoptosis, Ligand for E3 Ligase. Smiles: O(CC1=CC=C(CN2CCOCC2)C=C1)C3=C4C(C(=O)N(C4)[C@@H]5C(=O)NC(=O)CC5)=CC=C3. References: Matyskiela M E , Zhang W , Man H W , et al. A Cereblon Modulator...
| Keywords: | CC-220 |
| Application: | Antiinflammatory, Antineoplastic |
| CAS | 1323403-33-3 |
| MW: | 449.5 D |
From 38.00€
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Iberdomide
Item number: BPS-82009-1
Iberdomide is a derivative of Thalidomide and has antitumor and immunostimulatory activities because it is a potent cereblon (CRBN) E3 ligase modulator.
| Application: | Protac(R) reagent |
| CAS | 1323403-33-3 |
| MW: | 449,5 D |
From 1,081.00€
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