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Item number: Cay45324-1

A nonpeptide agonist of PKR1 and PAM of PKR2, increases intracellular calcium release and Akt phosphorylation in PKR1-expressing CHO cells (EC50 = 44 nM), enhances prokineticin-induced ERK phosphorylation in PKR2-expressing CHO cells at 1 nM, increases survival, reduces cardiac lesion formation, improves cardiac...

Keywords:	N-[(1Z)-2-(4-methoxyphenyl)-1-[[(3-pyridinylmethyl)amino]carbonyl]ethenyl]-benzamide
Application:	PKR1 nonpeptide agonist / PKR2 positive allosteric modulator (PAM)
CAS	1322013-92-2
MW:	387.44 D

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