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ACY-1215
ACY-1215

Item number: Cay21531-25

ACY-1215 is an inhibitor of the class IIb histone deacetylase (HDAC) HDAC6 (IC50 = 0.0047 µM). It is selective for HDAC6 over the class I HDACs HDAC1, -2, -3, and -8 (IC50s = 0.058, 0.048, 0.051, and 0.1 µM, respectively), class IIa HDACs HDAC4, -5, -7, and -9 (IC50s = 7, 5, 1.4 and >10 µM, respectively), class III...
Keywords: ACY-63, Ricolinostat, Rocilinostat, 2-(diphenylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]-5-pyrimidinecarboxamide
Application: HDAC6 inhibitor
CAS 1316214-52-4
MW: 433.5 D
From 99.00€ *
Review
Ricolinostat
Ricolinostat

Item number: TGM-T2489-100mg

Description: Ricolinostat (Rocilinostat) is an orally bioavailable, specific inhibitor of histone deacetylase 6 (HDAC6) with potential antineoplastic activity. Target: Apoptosis, HDAC. Smiles: ONC(=O)CCCCCCNC(=O)c1cnc(nc1)N(c1ccccc1)c1ccccc1. References: Santo L, et al. Blood, 2012, 119(11), 2579-2589.
Keywords: ACY-1215, Rocilinostat
Application: Targets histone deacetylase 6 [EC:3.5.1.98] (HDAC6)
CAS 1316214-52-4
MW: 433.5 D
From 43.00€ *
Review