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Afatinib-d6
Item number: Cay22552-1
Afatinib-d6 is intended for use as an internal standard for the quantification of afatinib (Cay-21567, Cay-11492) by GC- or LC-MS. Afatinib is an irreversible inhibitor of epidermal growth factor receptor (EGFR) and ErbB2 (IC50s = 0.5 and 14 nM, respectively). It increases the cytotoxicity of adriamycin in a...
| Keywords: | (2E)-N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-[di(methyl-d3)amino]-2-but... |
| Application: | Irreversible EGFR/ErbB2 inhibitor, GC-MS, LC-MS, internal standard |
| CAS | 1313874-96-2 |
| MW: | 492 D |
From 235.00€
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Afatinib D6
Item number: TGM-T10256-1mg
Description: Afatinib D6 (BIBW 2992 D6) is a deuterium-labeled Afatinib. Afatinib is an irreversible EGFR family inhibitor. Smiles: N(C=1C2=C(C=C(O[C@H]3CCOC3)C(NC(/C=C/CN(C([2H])([2H])[2H])C([2H])([2H])[2H])=O)=C2)N=CN1)C4=CC(Cl)=C(F)C=C4. References: Li D, et al. BIBW2992, an irreversible EGFR/HER2 inhibitor...
| Keywords: | BIBW 2992 D6 |
| CAS | 1313874-96-2 |
| MW: | 491.98 D |
187.00€
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