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Item number: TGM-T5468-100mg

Description: YF-2 is blood-brain-barrier permeable histone acetyltransferase activator, acetylates H3 in the hippocampus, CBP, PCAF, and GCN5 with EC50s of 2.75 µM, 29.04 µM and 49.31 µM , respectively. Target: Epigenetic Reader Domain, Others, Histone Acetyltransferase. Smiles:...

CAS	1311423-89-8
MW:	430.85 D

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YF-2

Item number: Cay31230-1

YF-2 is a histone acetyltransferase (HAT) activator. It inhibits proliferation of CCRF-CEM, Hs 578T, A549, and U251 cancer cells (IC50s = 88.7-286 µM), as well as multidrug-resistant NCI/ADR-RES cells (IC50 = 44.8 µM). YF-2 (5 mg/kg) increases reduced acetylated histone H3 levels in a mouse of model of Alzheimer's...

Keywords:	N-[4-chloro-3-(trifluoromethyl)phenyl]-2-[2-(dimethylamino)ethoxy]-6-ethoxy-benzamide
Application:	HAT activator
CAS	1311423-89-8
MW:	430.9 D

From 67.00€ *

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