3 products were found matching "1311367-27-7"!
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BIX 02565
Item number: Cay19183-1
The 90 kDa ribosomal S6 kinases (RSKs) are a group of serine/threonine kinases involved in diverse cellular processes, including growth, survival, and motility. Phosphorylation of the sodium-hydrogen exchanger (NHE) in cardiac tissue by RSK has been shown to activate NHE during cellular stresses, such as myocardial...
| Keywords: | (5R)-N-[1-[3-(dimethylamino)propyl]-1H-benzimidazol-2-yl]-2,3,4,5-tetrahydro-5-methyl-1-oxo-1H-[1,4]diazepino[1,2-a]indole... |
| Application: | RSK2 inhibitor |
| CAS | 1311367-27-7 |
| MW: | 458.6 D |
From 54.00€
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MBP146-78
Item number: SYN-1227-M100
MBP146-78 inhibits the growth of Eimeria spp. both in vitro and in vivo. The molecular target of MBP146-78 was identified as cGMP-dependent protein kinase (PKG) using a tritiated analogue to purify a approximately 120-kDa protein from lysates of Eimeria tenella. This represents the first example of a protozoal PKG....
| Keywords: | 4-[2-(4-Fluorophenyl)-5-(1-methylpiperidine-4-yl)-1H-pyrrol-3-yl] pyridine |
| Application: | Eimeria spp. cGMP-dependent protein kinase (PKG) inhibitor |
| CAS | 1311367-27-7 |
| MW: | 335.4 D |
From 108.00€
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BIX02565
Item number: SYN-1228-M001
Solid. Soluble in DMSO or ethanol. Slightly soluble (<1mg/ml) in water. TAK-632 is a potent pan-RAF inhibitor with favorable in vitro activity (BRAF(V600E) IC(50) of 2.4nM.
| Keywords: | TAK632 |
| Application: | pan-RAF inhibitor |
| CAS | 1311367-27-7 |
| MW: | 554,5 D |
From 139.00€
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