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Item number: Cay27739-1

PH-002 is an inhibitor of the interaction between the amino- and carboxy-terminal domains of apolipoprotein E4 (ApoE4, IC50 = 116 nM in a FRET reporter assay for domain interaction). It restores intracellular trafficking of ApoE4 to the endoplasmic reticulum and Golgi apparatus in Neuro-2a cells expressing...

Keywords:	4-[[4-[[2-(3,4-dihydro-3-methyl-4-oxo-1-phthalazinyl)acetyl]amino]phenyl]methyl]-1-piperazinecarboxylic acid,...
Application:	ApoE4 NT-CT-domain interaction inhibitor
CAS	1311174-68-1
MW:	491.6 D

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PH-002

Item number: TGM-T16518-100mg

Description: PH-002, an inhibitor targeting the intramolecular domain interaction of apolipoprotein (apo) E4 in neuronal cells, additionally enhances mitochondrial motility and promotes neurite outgrowth, thereby countering related impairments. Target: Others. Smiles:...

Application:	ApoE4 NT-CT-domain interaction inhibitor
CAS	1311174-68-1
MW:	491.58 D

From 42.00€ *

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