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Item number: Cay39292-1

BGJ398 is an orally available inhibitor of human FGFRs (IC50s = 0.9, 1.4, and 1 nM for FGFR1, FGFR2, and FGFR3, respectively). It inhibits FGFR4 and VEGFR2 with IC50 values of 60 and 180 nM, respectively, and displays comparatively little activity towards Abl, Fyn, Kit, Lck, Lyn, and Yes (IC50s = 0.3-2.5 µM). BGJ398...

Keywords:	Infigratinib (phosphate), NVP-BGJ398 (phosphate),...
Application:	Pan FGFR inhibitor
CAS	1310746-10-1
MW:	658.5 D

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Infigratinib Phosphate

Item number: LKT-I527211.25

NVP-BGJ398 is an inhibitor of FGFR that exhibits anticancer chemotherapeutic and antirachitic activities. NVP-BGJ398 inhibits cell viability in colon cancer cells and prevents progression and tumor formation in animal models of malignant rhabdoid tumors. In endometrial cancer cells, NVP-BGJ398 induces cell cycle...

Keywords:	NVP-BGJ398 Phosphate, BGJ-398 phosphate
Application:	FGFR inhibitor
CAS	1310746-10-1
MW:	658.5 D

From 201.00€ *

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