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Item number: Cay22074-10

VU036172 is a positive allosteric modulator of metabotropic glutamate receptor 5 (mGluR5, Ki = 195 nM). It is selective for mGluR5 over mGluR1, mGluR3, and mGluR4 at 10 µM. VU036172 (20 and 50 µM) prevents TNF-alpha and nitric oxide (NO) production by IFN-gamma- or LPS-stimulated BV-2 and primary microglial cells....

Keywords:	N-cyclobutyl-6-[2-(3-fluorophenyl)ethynyl]-3-pyridinecarboxamide, monohydrochloride
Application:	Positive allosteric mGluR5 modulator
CAS	1309976-62-2
MW:	330.8 D

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VU 0360172 hydrochloride

Item number: TGM-T23510-10mg

Description: positive allosteric modulator of mGlu5 receptors. Target: Others. Smiles: Cl.O=C(NC1CCC1)C2=CN=C(C#CC=3C=CC=C(F)C3)C=C2

CAS	1309976-62-2
MW:	330.78 D

From 263.00€ *

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